Last week I attended a fantastic course in London called Pain and
Pharmacology. You might be interested to know what I learnt about Paracetamol
Paracetamol like most medications is metabolised
mainly by enzymes in the liver. Paracetamol goes through two consecutive phases
of metabolization, after the first phase it becomes very toxic to the cells of
the liver but this is usually immediately rectified after the second phase of
metabolization is complete. During paracetamol overdose one of the key issues
is the that there are insufficient enzymes to maintain the second phase
metabolization and the toxic partially metabolised paracetamol causes toxic
damage to the liver. Indeed, treatment for paracetamol overdose required giving
patients an enzyme inducing agent to help the liver cope with completing
metabolizing the toxic partially metabolised paracetamol.
Interestingly I learned that alcohol also competes
with paracetamol for the same metabolising enzymes, hence why alcohol can be a
significant aggravating variable in overdose. Also, however because drinking
alcohol at same time as taking paracetamol will mean partially metabolised
paracetamol will remain in its toxic form for longer and therefore is
potentially harmful to the liver. It’s not exactly known how much damage this
will cause or for how long this would be repeated before causing significant
harm but this is probably something we should be advising our patients to avoid
if at all possible. We know from research that a concept known as ‘staggered
overdosing’ occurs whereby people take more than the recommended levels of
paracetamol (greater vthan 4g every 24 hours) and often this correlates with
people also drinking alcohol along side – this can be damaging over a period of
So my advice is do not take Paracetamol before you
head for the pub or before you go to bed for a hang-over cure. There is no
medication cure to prevent a hangover. You simply have to wait till your liver
is clear of the alcohol.
Ref: Pain & Pharmacology
Lecture with David Baker, UCO and A competency Framework for all Prescribers
Spring is in the air and changes are
afoot. As many of you already know, The Empire Hall is about to undergo some
long-awaited refurbishments to the kitchen, bathrooms and area to the rear of
the hall. This will mean that I will need to temporarily close my treatment
room from May until August of this year. While this will be an inconvenience,
we do have options available.
If you would like an appointment during this time, please call me, and I may be able to visit you at home with my portable plinth or in one of my other clinics in Pulborough or Oving.
Matt Hancock has published his vision for how he plans to transform the government’s approach to prevention, paving the way for a green paper in 2019.
You can find the full story online, but here are the highlights. Osteopaths has always championed the causes of disease, so this is really exciting for us. One of my big bug bears as a professional is the lack of personal care and responsibility British people have with their health compared to other nations. I think the NHS has had a part in this, because we have all at times relied on the NHS just being there to pick us up if something goes wrong, but it is time for change.
Matt Hancock said:
Two of the biggest health successes of the 20th century had prevention at their core: vaccination and cutting smoking. In the UK, both were achieved by careful and considered government intervention.
In the UK, we are spending £97 billion of public money on treating disease and only £8 billion preventing it across the UK. You don’t have to be an economist to see those numbers don’t stack up.
A focus on prevention and predictive medicine isn’t just the difference between life and death, it’s the difference between spending the last 20 years of your life fit and active, or in constant pain from a chronic condition. So our focus must shift from treating single acute illnesses to promoting the health of the whole individual. That requires more resources for prevention.
Duncan Selbie, Chief Executive, Public Health England said:
Investing in prevention is the smartest thing we can do. We need to move from a system that detects and treats illnesses to one that also predicts and prevents poor health through promoting health in all policies and puts people back in charge of their own health.
In response to my search for a Sponsorship partnership with a young rider, I am very excited to be working with Holly Fletcher and her talented horses No Problem (Billy) and Wrexford Imp (Foxy). Holly is very hard working and dedicated to her horses and his hoping to establish herself in Novice Eventing this year. I am very much looking forward to working with her to keep her horses in the best health possible. You can find out more about Holly’s activities on FaceBook, Instagram (@hf_eventing), Twitter (@HF_eventing_) and YouTube.
During the 142nd Session of its Executive Board meeting last month, the World Health Organization (WHO) voted to admit the Osteopathic International Alliance into official relations!!!
What does this mean?
“Official relations” is a privilege that the WHO “Executive Board may grant to nongovernmental organizations, international business associations and philanthropic foundations that have had and continue to have a sustained and systematic engagement in the interest of the Organization. The aims and activities of all these entities shall be in conformity with the spirit, purposes and principles of WHO’s Constitution, and they shall contribute significantly to the advancement of public health.